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Operative animation, Rigid cystoscopy, biopsy and fulguration

Rigid cystoscopy, cold-cup biopsy and fulguration

The rigid look under anaesthetic: a stable sheath, two telescopes, and a working channel wide enough to take a real bite of the bladder wall and to burn what bleeds.

This page is the stack, the survey, the biopsy taken cold so the histology survives, the fulguration that stays on the point, and the mapping biopsies that answer a positive cytology.

Core tier FRCS core urology, bladder cancer diagnosis Interactive 3D

Operative visualisation

Schematic scene preview: Rigid cystoscopy, biopsy and fulguration
Preparing the 3D anatomy…

UrOops3D · UroRef · © Nity G

Click me next Section 2 of 8 Anatomy The structures this operation works between, and the one it must not cross.

The structures in the scene

Rigid cystoscopy, biopsy and fulguration: how the structures relateThe bladder through the rigid sheath, 30 and 70 degree lenses. Bladder wall for biopsy and fulguration: sheath passes without push; forced, a false passage Bulbar urethra and sphincter (danger). Bladder wall for biopsy and fulguration: 30 degrees for the floor, 70 for the dome The two telescopes. Bladder wall for biopsy and fulguration: a bite or burn at an orifice obstructs the kidney Trigone and orifices (danger). Bladder wall for biopsy and fulguration: thinnest; biopsied half full, pressed not driven The dome (danger). Bladder wall for biopsy and fulguration: obturator territory; current jerks the leg The lateral walls (danger). Bladder wall for biopsy and fulguration: cup without current; electrodes in short bursts Cold cup, button and Bugbee electrodes.Bladder wall for biopsyand fulguration!Bulbar urethra andsphincterThe two telescopes!Trigone and orifices!The dome!The lateral wallsCold cup, button andBugbee electrodessheath passeswithout push;forced, a false…30 degrees for thefloor, 70 for thedomea bite or burn atan orificeobstructs the…thinnest; biopsiedhalf full, pressednot drivenobturatorterritory; currentjerks the legcup withoutcurrent; electrodesin short burstsTargetDangerLandmarkContext
The bladder through the rigid sheath, 30 and 70 degree lenses. Schematic, not to scale; relationships only.
  • The rigid sheath enters the bladder along the axis of the urethra, so the 30 degree lens sees the trigone and the posterior and lateral walls easily and the 70 degree lens is needed to look back at the dome and the anterior wall.
  • The working channel places the cup or the electrode just ahead of the lens, in the centre of the view, so what is biopsied or burnt is what is being looked at.
  • ›Bulbar urethra and sphincter - the curve the sheath follows and the ring it passes without push; the false passage is made here.
  • ›The two telescopes - 30 degrees for the survey and the working channel, 70 degrees for the dome and the anterior wall.
  • ›Trigone and orifices - the triangle on the floor with an orifice at each corner; seen before and after, never biopsied at the orifice.
  • ›The dome - the thinnest wall and the one a distended bladder thins further; biopsied half full, pressed not driven.
  • ›The lateral walls - obturator territory: current here can jerk the leg.
  • ›Cold-cup forceps - a mucosal bite with lamina propria, taken without current so the histology survives.
  • ›Button and Bugbee electrodes - coagulation at the point, short bursts, never painted across the wall.
Click me next Section 3 of 8 Steps The operation in order, with the landmark that guards each move.

Operative steps

  1. Before the sheath The indication: a tissue diagnosis that a flexible scope cannot make, a red patch or a flat lesion to biopsy, a positive cytology with nothing seen, a bleeding point to burn, or an examination the patient cannot tolerate awake. General or spinal anaesthetic, lithotomy in supports with the legs padded at the peroneal nerve and the buttocks at the end of the table. Antibiotics at induction where the urine or the history asks for them. The consent names infection, bleeding, urethral injury and the small chance of a perforation.
  2. The stack A 21 French sheath with its obturator, a bridge with a working channel, a 30 degree telescope for the survey and a 70 degree for the dome and anterior wall, the camera and light lead, irrigation of saline by gravity from a bag no higher than sixty centimetres. On the trolley: cold-cup biopsy forceps, the button or Bugbee electrode with the generator on coagulation, a ureteric catheter, specimen pots already labelled by site, and formalin. The plate goes on the thigh if monopolar diathermy is used.
  3. The sheath in under vision The sheath goes in on the visual obturator with the 30 degree lens looking through it, following the lumen: never blind, never forced. The bulbar urethra turns upward and the sheath is dropped between the legs to follow the curve. The sphincter is a closed ring that the anaesthetic relaxes; the sheath passes it without push. The veru, the prostatic urethra with its lobes, and the bladder neck are noted on the way through, and the obturator comes out for the bridge and the telescope.
    where it bites: a rigid sheath forced through a stricture or a closed sphincter makes a false passage; the fix is to withdraw and find the lumen with the lens.
  4. The survey The bladder is emptied and refilled to half. The air bubble at twelve o'clock orients the view; the trigone is on the floor with an orifice at each corner, each watched for a jet. The survey is in a fixed order: dome, anterior wall, right wall, posterior wall, left wall, floor. The 70 degree lens looks round the corner at the dome and the anterior wall that the 30 cannot reach, and suprapubic pressure from the assistant brings the dome down into view. A red velvety patch, a flat lesion, a diverticulum or a papillary tumour is described by wall, clock position and size before it is touched.
  5. The cold-cup biopsy The cold-cup forceps go through the bridge and are opened and pressed against the lesion so that the mucosa domes into the cup, then closed and pulled sharply away. The bite is mucosa with some lamina propria, taken without current so the histology is not burnt; a second bite from the same site if the first was small. Each bite goes straight into the pot labelled with its site. The site bleeds a little, which is expected and is dealt with once the specimen is safe.
    where it bites: a cold-cup bite at the thin dome of a distended bladder can go through the wall; the dome is biopsied with the bladder half full and the cup pressed, not driven.
  6. Fulguration The button or Bugbee electrode on coagulation is touched to the bleeding point, not painted across the wall, and a short burst is given until the point blanches. The current goes to where the electrode touches, and a distended bladder makes the wall thinner under it, so the bladder is kept half full. A small flat lesion can be fulgurated in full once its biopsy is taken; a papillary tumour is resected, not burnt, because burning destroys the stage. Fulguration near the lateral wall can stimulate the obturator nerve and jerk the leg: shorter bursts and lower power.
  7. Mapping biopsies When the cytology is positive and the bladder looks normal, or when carcinoma in situ is suspected, cold-cup bites are taken from named sites: the trigone, both lateral walls, the posterior wall and the dome, each in its own labelled pot, and the prostatic urethra with a loop or a cup. Nothing is biopsied at the orifice itself. The sites are drawn on a bladder map in the note so that a positive result can be placed. Random biopsies of a normal-looking bladder without a reason are not taken.
  8. Haemostasis and the check The irrigation is slowed and every biopsy site inspected; a spurting point is fulgurated, an ooze is left. Both orifices are seen again with their jets, because a bite or a burn near one can obstruct it. The bladder is emptied through the sheath and the sheath is withdrawn under vision with a last look at the prostatic urethra and the sphincter. A catheter is left only if the bleeding or the number of biopsies asks for it.
  9. The note and the specimens The note draws the bladder and marks every site with what was done there: biopsy, fulguration, both. The pots and the request forms match the map, site by site, and the number of pots is counted against the number of sites before the patient leaves theatre. The patient is warned about pink urine and burning for a few days and told when and how the histology will be given. The team that requested the biopsies chases the result.
Click me next Section 4 of 8 Danger zones Where this operation bites, and why it bites there.
Critical relationship

Danger zones

The spatial relationships the animation is built to make automatic. Before you read each one, ask yourself: at this point in the operation, what is about to go wrong, and what is my first move? The save for each sits in the Complications tab.

  • RiskThe dome of a full bladder - the thinnest wall, thinned further by distension; a cold cup or a burn here can perforate.
  • RiskThe ureteric orifices - a bite or a burn at the orifice obstructs the kidney; the site is chosen away from them.
  • RiskThe lateral wall - obturator territory; current here jerks the leg and, with a loop, perforates.
  • RiskThe sphincter and a stricture - a rigid sheath forced through either makes a false passage.
Practise it Take me into the scene Opens the animation at a danger moment and asks you to predict the mechanism and your first move before it reveals.
Click me next Section 5 of 8 Complications The save for each one: the first move, the escalation trigger, the op-note line.

Complications and immediate saves

Trigger each of these live in the Animation tab, then read the save: the first move, the escalation trigger, and the line that goes in the op note.

Perforation

  • a cold-cup bite or a burn at the dome of an over-full bladder has gone through: fat in the crater, irrigant not returning.
The save
  1. Stop. Empty the bladder through the sheath and do not refill it. first move
  2. Look at the site: fat means through; note whether the perforation is at the dome, where the peritoneum lies over, or lower down.
  3. A small extraperitoneal perforation: catheter for a week and a cystogram before it comes out.
  4. Peritonism, abdominal distension or a large irrigant deficit: the intraperitoneal one, and a laparotomy with senior help. escalation trigger
  5. Note: the site, extra- or intraperitoneal, the deficit, the catheter and the imaging plan. document

Bleeding that fills the field

  • a biopsy site spurting: the view goes red and the point is lost.
The save
  1. Slow the irrigation and let the field clear enough to see the point. first move
  2. Touch the button to the point on coagulation, short bursts, until it blanches.
  3. A field that will not clear: evacuate the clot with a bladder syringe, a catheter with irrigation, and senior help. escalation trigger
  4. Note: the site, the control achieved, the catheter and the irrigation plan. document

Orifice injury

  • a mapping bite or a burn taken at the orifice: the jet stops, the orifice cannot be seen.
The save
  1. Stop instrumenting that corner of the trigone. first move
  2. Try to cannulate the orifice with a ureteric catheter or wire and place a stent for four to six weeks.
  3. If it cannot be found, an ultrasound at two weeks and at three months for hydronephrosis.
  4. Loin pain, fever or a rising creatinine: image and drain the kidney by nephrostomy. escalation trigger
  5. Note: which orifice, what was done, stented or not, and the imaging plan. document

Urethral injury by the sheath

  • a rigid sheath forced through a stricture or a closed sphincter: blood, a false passage, no lumen ahead.
The save
  1. Withdraw and look for the true lumen with the 30 degree lens; never push blind. first move
  2. If the lumen is found, pass a wire and continue over it, or catheterise over it and abandon the procedure.
  3. If it is not found: a suprapubic catheter and the procedure another day. escalation trigger
  4. Warn the patient about a stricture and arrange follow-up.
  5. Note: where the injury is, the route used, and the plan. document

Obturator kick

  • current near the lateral wall stimulates the obturator nerve through the wall and the leg jerks.
The save
  1. Stop the current the moment the leg moves. first move
  2. Shorter bursts, lower power, a less full bladder, and the wall held still with the sheath.
  3. Check the wall for a perforation, which is the danger when a loop is being used rather than a button.
  4. For a resection at that site, the anaesthetist gives muscle relaxation or an obturator block. escalation trigger
  5. Note: the kick, the site, and whether the wall was checked. document
Click me next Section 6 of 8 Troubleshooting When the case turns: the problem, then the next move.

Intra-operative troubleshooting

When the case turns: the problem, then the next move.

  • ActionThe sheath will not pass the bulb - drop the sheath between the legs to follow the curve; the obturator and the lens, never force.
  • ActionCannot see the dome - change to the 70 degree lens and ask for suprapubic pressure.
  • ActionThe cup slides off a flat lesion - a less full bladder so the mucosa is loose, press the open cup so the mucosa domes into it, then close and pull.
  • ActionThe burn does nothing - check the plate and the generator setting; a coated electrode is cleaned or changed.
  • ActionThe leg jerks - obturator stimulation: stop, shorter bursts, lower power, less bladder filling.
  • ActionMore pots than sites, or fewer - stop and reconcile before the patient leaves theatre; an unlabelled biopsy is worthless.
Click me next Section 7 of 8 FRCS viva Say it out loud, then mark yourself against the model answer.

FRCS viva questions

The examiner stems this scene prepares you for. Try to answer out loud first, then reveal, and learn the discriminator, the detail that turns a pass into a strong pass.

QHow would you investigate and manage a patient with positive urine cytology and a normal flexible cystoscopy?reveal answer
  • Positive cytology with a normal-looking bladder means carcinoma in situ, a lesion missed at flexible cystoscopy, or upper-tract urothelial cancer until proved otherwise.
  • I would image the upper tracts with CT urography, and I would arrange a rigid cystoscopy under anaesthetic with mapping biopsies: cold-cup bites from the trigone, both lateral walls, the posterior wall and the dome, each in a separate labelled pot, and a biopsy of the prostatic urethra with a loop or cup, because carcinoma in situ involves the prostatic urethra in a proportion of men.
  • I would take the bites cold so the histology is interpretable, avoid the orifices, and draw a map in the note.
  • If enhanced cystoscopy such as blue light or narrow band imaging is available I would use it to target biopsies.
  • If the bladder biopsies and the prostatic urethra are negative and the CT is normal, I would proceed to bilateral retrograde studies with selective upper-tract cytology and ureteroscopy as indicated.
  • Carcinoma in situ found in the bladder is treated with induction and maintenance BCG.
Strong pass

Say all three

  • Naming the prostatic urethral biopsy and the upper-tract work-up
  • With separate labelled pots and a map
  • Rather than a vague "random biopsies"
Examiner note
Naming the prostatic urethral biopsy and the upper-tract work-up, with separate labelled pots and a map, rather than a vague "random biopsies".
QWhy is a bladder biopsy taken with a cold cup rather than a resectoscope loop?reveal answer
  • The cold cup takes a small mucosal sample with some lamina propria without electrical current, so there is no thermal artefact and the pathologist can assess the urothelium, the lamina propria and any invasion at that level.
  • That is what is wanted for a flat red patch, a suspected carcinoma in situ or a mapping biopsy, where the question is the presence and grade of flat disease rather than depth of invasion.
  • A loop biopsy with current chars the specimen and the small sample is often uninterpretable.
  • For a papillary or solid tumour the question is different: depth of invasion into detrusor decides the stage and the treatment, and only a resection with a loop that reaches muscle can answer it, with the base sent separately.
  • So the rule is cold cup for flat lesions and mapping, loop resection with detrusor for tumours, and a lesion that bleeds after a cold-cup bite is fulgurated afterwards so that the histology is safe before any current is used.
Strong pass

Say all three

  • Linking the instrument to the pathological question: flat disease and grade for the cup
  • Depth and detrusor for the loop
  • With current only after the specimen is taken
Examiner note
Linking the instrument to the pathological question: flat disease and grade for the cup, depth and detrusor for the loop, with current only after the specimen is taken.
QA patient develops abdominal pain and distension after a cystoscopy with dome biopsies. Manage this.reveal answer
  • This is a bladder perforation until proved otherwise, and at the dome an intraperitoneal one is likely because the peritoneum lies over it.
  • I would resuscitate, examine for peritonism, stop any irrigation, and confirm a catheter is draining; if it is not in, I would place one.
  • I would obtain a CT cystogram, which distinguishes an extraperitoneal leak, with contrast confined to the perivesical space, from an intraperitoneal one with contrast outlining bowel loops.
  • An extraperitoneal perforation is managed with catheter drainage for about a week and a cystogram before removal.
  • An intraperitoneal perforation with peritonism needs a laparotomy or laparoscopy, repair of the bladder in two layers with absorbable suture, washout and a catheter, with senior help.
  • I would treat with antibiotics, monitor for ileus and sepsis, and document the site, the type, the imaging and the plan.
  • Prevention is biopsying the dome with the bladder half full and the cup pressed rather than driven.
Strong pass

Say both

  • The CT cystogram to separate extra- from intraperitoneal
  • Knowing that the dome perforation is the intraperitoneal one that needs repair
Examiner note
The CT cystogram to separate extra- from intraperitoneal, and knowing that the dome perforation is the intraperitoneal one that needs repair.
QWhat is the obturator reflex and how do you prevent and manage it?reveal answer
  • The obturator nerve runs along the lateral pelvic wall, close to the lateral bladder wall near the ureteric orifice, and current passed through the wall there stimulates it directly, causing a sudden adduction of the thigh.
  • Under general anaesthesia without muscle relaxation, or under spinal anaesthesia, the reflex is not abolished.
  • The danger is with a resection loop: the jerk drives the loop through the wall and perforates the bladder, often intraperitoneally.
  • With a button electrode during fulguration the risk is smaller but the movement still disturbs the field.
  • I would prevent it by warning the anaesthetist when working on a lateral wall so that muscle relaxation is given, or an obturator nerve block is placed, by keeping the bladder less full, using short bursts and lower power, and by using bipolar energy where available.
  • If a kick occurs I would stop the current immediately and inspect the wall for a perforation before continuing.
Strong pass

Say both

  • Muscle relaxation or an obturator block arranged with the anaesthetist before lateral wall work
  • Inspecting for perforation after a kick
Examiner note
Muscle relaxation or an obturator block arranged with the anaesthetist before lateral wall work, and inspecting for perforation after a kick.
Click me next Section 8 of 8 Evidence The guidance each of these answers is built on.

Evidence and guidance

Two minutes

Close the lap: recall it before you leave.

Say it aloud, then reveal. Reading is not remembering.

  1. 01 The relationship Say the critical spatial relationship out loud, then reveal. reveal
    Memory frame

    The rigid sheath enters the bladder along the axis of the urethra, so the 30 degree lens sees the trigone and the posterior and lateral walls easily and the 70 degree lens is needed to look back at the dome and the anterior wall.

    Why?
    The working channel places the cup or the electrode just ahead of the lens, in the centre of the view, so what is biopsied or burnt is what is being looked at.
  2. 02 The first move Perforation. Your first move? reveal
    First move

    Stop.

    More detail
    Empty the bladder through the sheath and do not refill it.
  3. 03 The escalation trigger Perforation. What makes you call for help? reveal
    Escalate when

    Peritonism, abdominal distension or a large irrigant deficit: the intraperitoneal one, and a laparotomy with senior help.

  4. 04 The discriminator What turns a pass into a strong pass? reveal
    Strong pass

    Say all three

    • Naming the prostatic urethral biopsy and the upper-tract work-up
    • With separate labelled pots and a map
    • Rather than a vague "random biopsies"
    Examiner note
    Naming the prostatic urethral biopsy and the upper-tract work-up, with separate labelled pots and a map, rather than a vague "random biopsies".
  5. 05 The pitfall Where does this operation bite first? reveal
    Pitfall

    The dome of a full bladder

    Why?
    the thinnest wall, thinned further by distension; a cold cup or a burn here can perforate.

Revision practice with self-marked answers, not an assessment of clinical competence. Kept in this browser only; it does not sync between devices.